Familial Amyloid Polyneuropathy

What is Familial Amyloid Polyneuropathy? Familial Amyloid Polyneuropathy (FAP) is an inherited disease that causes progressive sensorimotor and autonomic nerve disorder. Peripheral nerve degeneration (polyneuropathy) begins in small fibers, resulting in sensory symptoms of numbness, burning, and tingling — typically in the feet. This progresses to larger nerve fibers, which leads to muscle weakness and …

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